JEOL 2100


The Hafenstein Lab would like to announce the Grand Opening of the new, Imaging Core for Biological Research. The design and development of the new imaging core was supported by Vice Dean of Research, Daniel Notterman, Penn State College of Medicine. In the new state of the art microscopy suite are three components that will bring high end cryoEM biological structural imaging research to Penn State University. The new lab is contained within a controlled environment to minimize humidity, temperature fluctuation, and acoustic noise. The Cryo JEOL 2100 transmission electron microscope is the cornerstone of the operation capable at running up to 200kV. Coupled with the TEM is a Gatan Ultrascan 4000 4k CCD for collecting high resolution data, and a data processing suite for completing 3D EM maps. Funds to acquire the new CryoEM were awarded by the NIH, Shared Instrumentation Grant to Dr. Hafenstein, Director of the CryoEM Core.


JEOL 1400

Our JEOL 1400 TEM produces high-resolution images from its bottom-mount GATAN camera, which collects data suitable for 3D Reconstructions.

  • Tissue Processing and Embedding
  • Thin Section Staining
  • Negative Staining
  • Multiplexed Immunolabeling with sized Gold Conjugates

Wet lab space and equipment for:

  • Molecular Biology
  • Sample Preparation
  • Specialty Grid Preparation
  • Tissue Culture
  • Virus Purification


GATAN CP3 Cryo Plunge for cryo fixation